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Updated: Aug 17, 2026

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A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus
Published on: June 23, 2022
A degenerative encephalomyelopathy in 7 Kuvasz puppies
Murray J Hazlett1, Laura L Smith-Maxie, Alexander de Lahunta
1Animal Health Laboratory, University of Guelph, Guelph, Ontario. mhazlett@uoguelph.ca
Abstract:
Seven Kuvasz puppies from 2 same-parentage litters developed weakness and ataxia. Six necropsied dogs had lesions in caudate nucleus, cerebellar nuclei and folia, and spinal cord. Lesions seen were felt to be familial or due to the effects of an amprolium-induced thiamine deficiency on the developing brains of these puppies.

