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Updated: Aug 2, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

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Published on: May 14, 2013

Sirolimus-eluting stents associated with paradoxic coronary vasoconstriction

Mario Togni1, Stephan Windecker, Rosangela Cocchia

  • 1Swiss Cardiovascular Center Bern, Bern, Switzerland.

Journal of the American College of Cardiology
|July 19, 2005
PubMed
Summary

Sirolimus-eluting stents (SES) did not impair exercise-induced vasodilation in adjacent coronary arteries. However, SES implantation caused paradoxical vasoconstriction in these segments, suggesting drug-induced endothelial dysfunction.

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