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Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Systolodiastolic variations of blood flow during central retinal vein occlusion: exploration by dynamic angiography

M Paques1, O Baillart, O Genevois

  • 1Department of Ophthalmology, Fondation Ophtalmologique Rothschild, 25 rue Manin, 75019 Paris, France. michel.paques@laposte.net

The British Journal of Ophthalmology
|July 19, 2005
PubMed

Insights

Pulsatile venular outflow (PVO) in central retinal vein occlusion (CRVO) patients occurs due to distinct hemodynamics. Second order vein flow synchronizes with arterial flow, while first order veins show delayed peak flow.

Area of Science:

  • Ophthalmology
  • Vascular Biology
  • Medical Imaging

Background:

  • Acute central retinal vein occlusion (CRVO) can present with pulsatile flow in large retinal veins, termed pulsatile venular outflow (PVO).
  • Understanding the mechanism of PVO is crucial for managing CRVO and its associated visual disturbances.

Purpose of the Study:

  • To investigate the underlying hemodynamic mechanism responsible for pulsatile venular outflow (PVO) in patients with central retinal vein occlusion (CRVO).

Main Methods:

  • Quantitative and qualitative analysis of dynamic angiograms in 10 patients with CRVO and PVO.
  • Correlation of temporal venous flow patterns in first and second order veins with the cardiac systolic cycle.

Main Results:

  • Pulsatile venular outflow (PVO) onset occurred shortly after arterial systole (less than 0.08 seconds).
  • PVO onset was simultaneous with minimal flow (Vmin) in first order veins.
  • Maximal flow (Vmax) in first order veins was delayed, occurring 0.20-0.44 seconds after PVO onset.

Conclusions:

  • Pulsatile venular outflow (PVO) in CRVO results from distinct hemodynamic conditions in different venous orders.
  • Second order vein flow appears synchronous with arterial flow.
  • Delayed peak flow in first order veins suggests a role for intraocular pressure dynamics or venous compression.
Abstract

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