Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cognitive influences on predictive saccadic tracking.

E Isotalo1, A G Lasker, D S Zee

  • 1Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD 21287-6921, USA.

Experimental Brain Research
|July 19, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preface.

Progress in brain research·2022
Same author

Consensus Paper: Neurophysiological Assessments of Ataxias in Daily Practice.

Cerebellum (London, England)·2018
Same author

Ocular stability and set-point adaptation.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2017
Same author

Eye movements in vestibular disorders.

Handbook of clinical neurology·2016
Same author

The cerebellum in eye movement control: nystagmus, coordinate frames and disconjugacy.

Eye (London, England)·2015
Same author

The cerebellum in eye movement control: nystagmus, coordinate frames and disconjugacy.

Eye (London, England)·2014
Same journal

Changes in synergy formation and modulation during cyclic finger force production tasks in female adults with dystonic cerebral palsy.

Experimental brain research·2026
Same journal

Molecular links between reelin downregulation, topoisomerase IIβ alterations, and proteins involved in Alzheimer pathology in human SH-SY5Y neuroblastoma cell line.

Experimental brain research·2026
Same journal

Motor cortex excitability during spine shape-judgment in adolescent idiopathic scoliosis: a TMS motor evoked potential study.

Experimental brain research·2026
Same journal

Trajectory dynamics and endpoint accuracy in targeted ballistic contractions.

Experimental brain research·2026
Same journal

Exploring Sevoflurane promotes hippocampal neuron mitophagy in elderly postoperative cognitive dysfunction by HSP90AA1 based on network pharmacology.

Experimental brain research·2026
Same journal

Loading modulates monosynaptic transmission from spindle primary afferents to motoneurons in humans.

Experimental brain research·2026
See all related articles

Mental set significantly impacts eye movement prediction. Active, volitional instructions enhance predictive and anticipatory saccades, while passive instructions yield more reflexive saccades, especially with longer intervals and larger displacements.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Ophthalmology

Background:

  • Predictive capabilities in human eye movements are crucial for visual perception.
  • Understanding the influence of cognitive factors on motor control is essential.

Purpose of the Study:

  • To investigate how mental set, induced by different instructions, affects predictive saccade behavior.
  • To analyze the impact of target amplitude and inter-stimulus interval (ISI) on saccade characteristics.

Main Methods:

  • Utilized a saccade square-wave tracking paradigm with ten healthy subjects.
  • Compared three target amplitudes (10, 20, 40 degrees) and five ISIs (400-2000 ms).
  • Assigned either passive ('follow the lights') or active ('move eyes in time') instructions.

Related Experiment Videos

Main Results:

  • Active instructions led to more predictive and anticipatory saccades; passive instructions led to more reflexive saccades.
  • The effects of mental set were most pronounced with longer ISIs (1000, 2000 ms) and larger amplitudes (40 degrees).
  • Active instruction allowed subjects to better time eye arrival to target appearance, irrespective of amplitude.

Conclusions:

  • Cognitive set, dictated by instructions, profoundly influences predictive saccade behavior.
  • Findings have significant implications for interpreting neural correlates of predictive behavior in healthy individuals and neurological patients.