Related Experiment Video
Updated: Aug 16, 2026

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
Published on: October 20, 2021
Pemphigus following hepatitis B vaccination--coincidence or causality?
Yackov Berkun1, Daniel Mimouni, Yehuda Shoenfeld
1Department of Pediatrics, Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Israel.
Abstract:
Pemphigus is an autoimmune blistering disease caused by autoantibodies against epithelial intercellular components. Its etiology is unknown, and neoplasms, antecedent infections or medications are considered possible triggering factors for the disease in some cases. We describe the first case of pemphigus following a hepatitis B virus vaccination. We suggest that in some cases vaccination may be the triggering factor for pemphigus in genetically predisposed individuals and physicians should be aware of this possible association.
Related Concept Videos
Hepatitis
Cross-reactivity
Vaccinations
Chickenpox
Viral Hepatitis I: Introduction
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
