Related Experiment Video
Updated: Aug 16, 2026

High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
Published on: July 17, 2014
Plasmodium parasite proteins and the infected erythrocyte
Kasturi Haldar1, N Luisa Hiller, Christiaan van Ooij
1Departments of Pathology and Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA. k-haldar@northwestern.edu
Abstract:
Erythrocyte modification by malaria proteins is linked to both disease severity and infection. In this issue of Trends in Parasitology, Templeton and Deitsch, and Horrocks and Muhia discuss recent work identifying a host-targeting (HT) signal on malaria proteins. This signal predicts a secretome of 300-400 effectors for the human malaria parasite Plasmodium falciparum, vastly expanding the number of potential vaccine and drug targets. The HT signal seems to be distinct from known cellular transport signals, which suggests that it might be a novel eukaryotic secretion signal.
Related Concept Videos
Malaria
Symbiosis
Diversity of Protists II
Amebiasis
Diversity of Protists IV
Fungal Phylum Microsporidia

