[Pathohistological changes characteristic for endometrial hyperplasia]

Peculiarities of endometrial hyperplasia during monophase menstrual cycle have been investigated. 52 patients of premenopause and menopause period (age 35-52 years old) have been investigated using uterus scrape analysis. Histostereometric and morphometric methods have been used for the study. The analyses of the obtained results has shown that: 1. The endometrial hyperplasia accompanies the shortened and prolonged persistency of follicles in a monophase menstrual cycle. Therefore when making the pathohistological diagnosis, the pathogenetic aspects should be indicated; 2. Endometrial hyperplasia is not a separate nosological phenomenon and effectiveness of its therapy strongly depends on the condition of ovary and hormone systems.