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Updated: Aug 16, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
[Comparative study by pH-tests of the efficacy of antimicrobial agents in oral cavity]
Abstract:
The opportunity of use stimulated by sucrose solutions and urea test pH changes of the mixed saliva were investigated with the purpose of an estimation of efficiency of antiseptic and hygienic means action. Research is carried out on 37 students who have been specially picked up in 3 groups: "A" -- with low activity of caries without periodontitis, "B" -- caries-susceptible and "C" -- with gingivitis and periodontitis. It appeared possible with the help of pH-measuring of saliva to compare antiseptic action in an oral cavity of 4 popular antiseptics: the combined gel with chlorhexidine and metronidazole, and also anticarious toothpaste in the form of application and in combination with cleaning teeth by a brush. The offered tests allow to reveal primary action of antiseptic means for the microflora causing either caries or inflammatory periodontal disease.
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Antimicrobial Effectiveness
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