Related Experiment Video
Updated: Aug 2, 2026

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
Published on: January 18, 2011
[Domiciliary non-invasive ventilation in children]
1Service de pneumologie pédiatrique et INSERM U 719, Hôpital Armand Trousseau, Assistance Publique, Hôpitaux de Paris, Paris, France. brigitte.fauroux@trs.ap-hop-paris.fr
Insights
Non-invasive positive pressure ventilation (NPPV) offers significant benefits for children with chronic respiratory insufficiency. Further research is needed to optimize NPPV use and improve quality of life.
Area of Science:
- Pediatric respiratory medicine
- Critical care
- Pulmonology
Context:
- Non-invasive positive pressure ventilation (NPPV) is a key ventilatory support technique for pediatric patients.
- Various conditions like neuromuscular diseases and airway obstructions cause chronic respiratory insufficiency in children, often leading to alveolar hypoventilation.
- NPPV can effectively manage alveolar hypoventilation in pediatric populations.
Purpose:
- To highlight the current understanding and limitations of NPPV in pediatric care.
- To emphasize the need for more physiological studies on NPPV in children.
- To define optimal NPPV modes and settings for specific pediatric pathologies.
Summary:
- Current criteria for initiating NPPV in children are primarily based on consensus guidelines for neuromuscular disorders.
- There is a lack of comprehensive physiological studies detailing NPPV's effects in pediatric patients.
- Further evaluation is required to establish precise indications and benefits of NPPV.
Impact:
- Enhanced understanding of NPPV's medium and long-term physiological effects on pediatric respiratory systems.
- Improved assessment of NPPV's impact on psycho-neurological development and overall quality of life for children.
- Potential for wider adoption of home-based NPPV with technological advancements and better evidence.
Introduction:
Non-invasive positive pressure ventilation (NPPV) represents a particularly interesting technique of ventilatory support in paediatrics. Indeed, a significant number of pathologies that may be responsible for chronic respiratory insufficiency in childhood, such as neuromuscular diseases, obstruction of the upper airways, disorders of chest wall and/or the lungs, and disorders of ventilatory control may all lead to alveolar hypoventilation that can be improved by ventilatory support.
Background:
Few physiological studies have been performed on NPPV in children. The most appropriate modes and settings for each pathology have not been clearly defined, and the criteria for commencing NPPV are based essentially on consensus guidelines for the management of neuromuscular disorders.
Viewpoint:
All the health care professionals managing these children should combine their efforts to evaluate more precisely the medium and long-term physiological effects of NPPV on the respiratory muscles, the development of the respiratory system, inspiratory activity, the indications for starting treatment and, above all, the benefits in terms of psycho-neurological development and quality of life.
Conclusions:
A better evaluation of the medium and long-term physiological and psychological benefits together with technical improvements in ventilators and associated equipment should allow a rapid expansion in the use of domiciliary NPPV in children.
Related Concept Videos
Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Respiratory Syncytial Virus Disease

