Fiber-optic-bundle-based optical coherence tomography
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Updated: Aug 16, 2026

High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging
Published on: January 11, 2011
Tuqiang Xie1, David Mukai, Shuguang Guo
1Beckman Laser Institute, Department of Biomedical Engineering, Pulmonary and Critical Care Division, UC Irvine Medical Center, University of California, Irvine, Irvine, California 92612, USA. txie@uci.edu
Abstract:
A fiber-optic-bundle-based optical coherence tomography (OCT) probe method is presented. The experimental results demonstrate this multimode optical fiber-bundle-based OCT system can achieve a lateral resolution of 12 microm and an axial resolution of 10 microm with a superluminescent diode source. This novel OCT imaging approach eliminates any moving parts in the probe and has a primary advantage for use in extremely compact and safe OCT endoscopes for imaging internal organs and great potential to be combined with confocal endoscopic microscopy.

