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Identification of a new HLA-B variant, HLA-B*5615
S Frison1, E Longhi, A E de Arias
1Dipartimento Trasfusionale e di Riferimento per i Trapianti di Organi, Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena-Fondazione IRCCS di Natura Pubblica, Milano, Italy.
Abstract:
A new HLA-B allele, B*5615, has been identified in a Caucasian individual by sequence-based typing. This allele shows a sequence identical to that of HLA-B*5601 except for two nucleotide substitutions that cause a change from TTA to TAC at codon 116 and an amino acidic change from Leucine to Tyrosine in the mature protein.
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