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Updated: Aug 9, 2026

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Discrimination of Seven Immune Cell Subsets by Two-fluorochrome Flow Cytometry
Published on: March 5, 2019
New developments in flow cytometric analyses of lymphocyte markers
T J Kipps1, G Meisenholder, B A Robbins
1Department of Medicine, University of California, San Diego, La Jolla.
Clinics in Laboratory Medicine
|June 1, 1992
Summary
This guide explains clinical flow cytometry, a vital diagnostic tool. It covers technical methods for setting up and running a lab, focusing on chronic lymphoproliferative diseases.
Area of Science:
- Clinical Laboratory Science
- Immunology
- Hematology
Background:
- Clinical flow cytometry is a rapidly advancing field with significant clinical and investigative applications.
- Accurate diagnosis and monitoring of diseases rely on robust laboratory methodologies.
Purpose of the Study:
- To provide a practical overview of the technical and methodologic aspects of clinical flow cytometry.
- To discuss the application of flow cytometry in diagnosing and monitoring chronic lymphoproliferative diseases.
- To serve as a guide for establishing and maintaining clinical flow cytometry laboratories.
Main Methods:
- Overview of fundamental features and practical aspects of clinical flow cytometry.
- Discussion of technical and methodologic considerations for laboratory setup and operation.
- Exploration of flow cytometry applications in specific disease contexts.
Main Results:
- Provides a comprehensive understanding of clinical flow cytometry principles and practices.
- Highlights the utility of flow cytometry in the diagnosis and management of lymphoproliferative disorders.
- Offers practical guidance for laboratory personnel.
Conclusions:
- Clinical flow cytometry is an essential tool for modern diagnostics and research.
- Proper implementation of technical and methodologic standards ensures reliable results.
- This article serves as a valuable resource for professionals in the field.

