Related Experiment Video
Updated: Aug 16, 2026
Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Combined myocardial and mesenteric surgical revascularization
Michel Kindo1, Arnaud Mommerot, Guillaume Maxant
1Department of Cardiovascular Surgery, Hôpital Civil, Strasbourg, France.
Insights
This study presents a successful one-stage surgical treatment for patients with both chronic mesenteric ischemia and coronary artery disease. Combined revascularization of the heart and mesenteric arteries offers a promising solution for selected individuals.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Gastroenterology
Background:
- Chronic mesenteric ischemia (CMI) often coexists with coronary artery disease (CAD).
- Myocardial ischemia poses significant risks post-splenic artery revascularization.
- Optimal treatment for combined CMI and myocardial ischemia remains undetermined.
Observation:
- A 57-year-old male patient presented with concomitant CMI and CAD.
- The patient underwent simultaneous revascularization of the left anterior descending coronary artery and superior mesenteric artery using venous grafts to the ascending aorta.
Findings:
- The patient experienced no symptoms at a 3-year follow-up.
- This outcome supports the efficacy of combined revascularization.
Implications:
- One-stage combined myocardial and mesenteric revascularization is a viable option for select symptomatic patients.
- This approach may improve outcomes in patients with concurrent CMI and CAD.
- Further research is warranted to establish guidelines for combined revascularization.
Abstract:
Chronic mesenteric ischemia is a rare disorder that is frequently associated with coronary artery disease. Myocardial ischemia is a leading cause of morbidity and mortality after revascularization of the splanchnic arteries. The optimal treatment of concomitant chronic mesenteric ischemia and myocardial ischemia is unknown. We report a case of this condition in a 57-year-old man who required revascularization of both the left anterior descending coronary and superior mesenteric arteries with venous grafts anastomosed to the ascending aorta. The patient remains asymptomatic after a 3-year follow-up. This good result argues for one-stage combined myocardial and mesenteric revascularization in selected symptomatic patients.
