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Published on: December 26, 2015
Evaluation of software-based telephone counseling to enhance medication persistency among patients with multiple
Bruce A Berger1, Huigang Liang, Karen Suchanek Hudmon
1Pharmacy Care Systems, 128 Miller Hall, Auburn University, AL 36849-5506, USA. bergeba@mail.auburn.edu
Objective:
To evaluate the effect of a software-supported intervention based on the Transtheoretical Model of Change and motivational interviewing on decreasing discontinuation (or increasing persistency) of Avonex (interferon beta-1a--Biogen), a medication for treatment of multiple sclerosis (MS).
Design:
Randomized controlled experimental design comparison of software-based telephone counseling (intervention group) and standard care (control group).
Setting:
United States.
Participants:
366 patients with MS.
Intervention:
Software-based telephone counseling.
Main Outcome Measure:
Discontinuation of Avonex treatment and movement among stages of the Transtheoretical Model of Change.
Results:
Patients in the software intervention group demonstrated a statistically significantly lower proportion of Avonex treatment (1.2%) discontinuation than the standard care group (8.7%). In addition, stage movement away from discontinuation of Avonex (i.e., toward continuation of therapy) was significantly higher in the treatment group.
Conclusion:
The Transtheoretical Model of Change constructs and motivational interviewing processes were effectively incorporated into a software-based intervention program, and this significantly decreased the proportion of patients who discontinued treatment of MS with Avonex. The integration of behavioral theory with information systems offers a promising approach for pharmacists and other providers to promote medication persistency.