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Updated: Aug 16, 2026

Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass
Published on: May 27, 2022
[Study on the extraction process for cannabinoids in hemp seed oil by orthogonal design]
Gang Zhang1, Jiangning Guo, Kaishun Bi
1North-east University, Shenyang.
Objective:
To select the optimum extracting procedure for cannabinoids from hemp seed oil.
Methods:
The optimum extracting procedure was selected with the content of cannabinol and delta9-tetrehydrocannabinol from hemp seed oil by orthogonal test design. We have examined three factors that may influence the extraction rate: the time of extraction, the times of extraction and the amount of methanol.
Results:
The optimum extraction condition was adding 5 ml, two times amount of methanol into hemp seed oil for 15 min.
Conclusion:
The above extraction process gave the most rational, stable, feasible and satisfactory results. The method is convenient.
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