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[Immunomodulation in cancer. What do we do and where do we go?]
Alain R Rodríguez Orozco1, Nicolas Medina Serriteño
1Retorno del Colegio Militar 145, Col. Chapultepec Sur, Morelia, Michocan, CP. arorozco@hotmail.com
Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|September 15, 2005
Summary
Cancer treatment is evolving towards targeted immunomodulation therapies. Biological response modifiers (BRMs) show promise alone or with traditional treatments for cancer control.
Area of Science:
- Oncology
- Immunology
Context:
- Recent advances in cancer research necessitate novel therapeutic strategies.
- Understanding the complex interplay between the immune system and tumors is crucial.
Purpose:
- To review the general principles of anti-tumor immune responses.
- To discuss tumor immune evasion mechanisms and host defense strategies.
- To evaluate the effectiveness and safety of biological response modifiers (BRMs) and immunomodulation therapies in cancer treatment.
Summary:
- The article explores the immune response against tumors, including immune evasion tactics employed by cancer cells and the body's defense mechanisms.
- It reviews current data on the efficacy and adverse events associated with BRMs and immunomodulation therapies.
- Biological response modifiers are presented as effective options for cancer treatment, potentially augmenting conventional therapies.
Impact:
- Immunomodulation therapies, including BRMs, represent a promising frontier in oncology.
- These therapies offer effective strategies for managing malignant diseases, either as standalone treatments or in conjunction with chemotherapy, surgery, or radiation.