Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The External RNA Controls Consortium: a progress report.

Shawn C Baker1, Steven R Bauer, Richard P Beyer

  • 1Illumina, Inc., 9885 Towne Centre Drive, San Diego, California 92121, USA.

Nature Methods
|September 24, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of birth weight with general obesity, central obesity, and MASLD in a nationally representative sample of US adolescents: A cross-sectional study from NHANES 1999 to 2020.

Medicine·2026
Same author

Risk factors for drug-induced liver injury in tuberculosis patients: a meta-analysis and systematic review.

Frontiers in medicine·2026
Same author

Numerical Simulation of the Influence of Structural Parameters on the Performance of a Direct Sodium Formate/Sodium Persulfate Microfluidic Fuel Cell.

ACS omega·2026
Same author

Timing impact of single shot femoral nerve block on rebound pain in patients undergoing total knee arthroplasty: a prospective randomized controlled trial.

Frontiers in medicine·2026
Same author

Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer.

Nature communications·2026
Same author

A chemiluminescent imaging immunosensor based on copper-doped NiFe PBA nanozyme for detection of BTN3A2: A candidate biomarker in early stage of gastric cancer.

Biosensors & bioelectronics·2026
Same journal

ClairS: a deep-learning method for long-read tumor-normal pair somatic small variant calling.

Nature methods·2026
Same journal

RNAbpFlow: base pair-augmented SE(3) flow matching for conditional RNA 3D structure generation.

Nature methods·2026
Same journal

Spatio-DARLIN enables robust and efficient in situ lineage tracing in mice at single-cell resolution.

Nature methods·2026
Same journal

EasyGrid: a versatile platform for automated cryo-EM sample preparation and quality control.

Nature methods·2026
Same journal

Cloud-based microscope enables live neuroimaging for 24 h and beyond with worldwide access.

Nature methods·2026
Same journal

Deep molecular profiling in three dimensions.

Nature methods·2026
See all related articles
This summary is machine-generated.

Standardized controls enhance data quality and acceptance in research and clinical labs. The External RNA Controls Consortium (ERCC) is creating industry-wide standards for expression assays.

Area of Science:

  • Molecular Biology
  • Biotechnology
  • Genomics

Background:

  • Standardized controls are crucial for validating data quality in research, preclinical, and clinical laboratory settings.
  • Best practice guidelines facilitate the acceptance of experimental data across scientific disciplines.

Purpose of the Study:

  • To introduce the development of industry-wide standard controls for expression assays.
  • To highlight the role of the External RNA Controls Consortium (ERCC) in establishing these standards.

Main Methods:

  • Development of commonly agreed-upon controls.
  • Testing of these controls for reliability and consistency.

Main Results:

  • The External RNA Controls Consortium (ERCC) is creating a universally accepted set of controls.

Related Experiment Videos

  • These controls aim to ensure consistent and reliable data evaluation in expression assays.

    • Conclusions:

    • The ERCC's initiative represents a significant step towards industry-wide standardization in expression assays.
    • Implementing these standard controls will advance the reproducibility and acceptance of laboratory data.