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Metastatic angiosarcoma to the thyroid.

S P Eng1, C H K Goh, J B K Khoo

  • 1Changi General Hospital, Department of Otolaryngology, Head & Neck Surgery, 2 Simei Street 3, Singapore 529889, Singapore. soh_ping_eng@cgh.com.sg

Revue De Laryngologie - Otologie - Rhinologie
|September 27, 2005
PubMed
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Metastatic angiosarcoma (AS) to the thyroid is rare but possible. This case highlights diagnostic challenges and treatment strategies for this aggressive cancer, including brachytherapy for pyriform fossa tumors.

Area of Science:

  • Oncology
  • Pathology
  • Radiotherapy

Background:

  • Angiosarcoma (AS) is a rare vascular tumor.
  • Metastatic AS to the thyroid is exceptionally uncommon, especially in non-alpine regions.
  • This case report addresses the diagnostic and management complexities of metastatic AS to the thyroid.

Observation:

  • A Chinese male patient presented with metastatic AS to the thyroid one year post-scalp AS radiotherapy.
  • Rapid metastasis expansion led to dysphagia and hemoptysis due to pyriform fossa invasion.
  • Fine-needle aspiration cytology was inconclusive, necessitating hemithyroidectomy for definitive diagnosis via paraffin histology.

Findings:

  • Histopathological examination confirmed angiosarcoma metastasis to the thyroid.
  • The patient received external beam radiotherapy for the pyriform fossa tumor, followed by brachytherapy via nasogastric tube.

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  • Despite treatment, the patient died four months later from unrelated cardiac failure.

    • Implications:

    • Metastatic angiosarcoma to the thyroid, though rare, should be considered in differential diagnoses.
    • Acute presentations of metastatic AS can pose diagnostic challenges, requiring advanced histopathological analysis.
    • Brachytherapy delivered via nasogastric tube offers a viable treatment option for pyriform fossa tumors.