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Non-syndromic multiple supernumerary teeth transmitted as an autosomal dominant trait
1Division of Orthodontics, Department of Dental Surgery, All India Institute of Medical Sciences, New Delhi, India.
Summary
Multiple supernumerary teeth, or extra teeth, can run in families. This study identifies a rare instance where this condition appears as a non-syndromal trait with autosomal dominant inheritance.
Area of Science:
- Dentistry
- Human Genetics
- Oral Pathology
Background:
- Supernumerary teeth are relatively common dental anomalies.
- Multiple supernumerary teeth are often linked to genetic syndromes like cleidocranial dysplasia and Gardner syndrome.
Observation:
- This study details a family exhibiting multiple supernumerary teeth.
- The affected individuals in this family show no other associated diseases or syndromes.
Findings:
- The occurrence of multiple supernumerary teeth as a non-syndromal trait was observed within the family.
- The inheritance pattern suggests an autosomal dominant transmission for this non-syndromal form of multiple supernumerary teeth.
Implications:
- This finding introduces a novel genetic transmission pattern for multiple supernumerary teeth.
- Understanding this non-syndromal inheritance may aid in genetic counseling and diagnosis for affected families.