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Unusual position-sensitive jaw tremor responsive to botulinum toxin
1Parkinson's Disease and Movement Disorders Center, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA. dtarsy@bidmc.harvard.edu
Summary
A focal jaw tremor, exacerbated by specific jaw positions, was observed in a patient. Botulinum toxin injections effectively reduced this movement disorder.
Area of Science:
- Neurology
- Movement Disorders
Background:
- Jaw tremor can significantly impact quality of life.
- Understanding the pathophysiology of focal tremors is crucial for effective treatment.
Observation:
- A case study of a woman presenting with a focal, position-sensitive jaw tremor.
- The tremor occurred when the jaw was slightly open or during drinking.
Findings:
- Electromyography revealed a 5 Hz rhythmic, alternating tremor in the masseter and digastric muscles.
- Normal reciprocal inhibition was noted, suggesting a specific tremor mechanism.
- Botulinum toxin injections led to a marked reduction in tremor severity.
Implications:
- Botulinum toxin is a potential therapeutic option for focal jaw tremors.
- This case highlights the importance of detailed clinical and electrophysiological assessment.
- Further research into the neurophysiological underpinnings of such tremors is warranted.