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Hydrolysed milk in preterm infants: an open problem.

Antonio A Zuppa1, Federica Visintini, Francesco Cota

  • 1Division of Neonatology, Department of Paediatrics, Catholic University of the Sacred Heart, Rome, Italy. zuppaaa@rm.unicatt.it

Acta Paediatrica (Oslo, Norway : 1992). Supplement
|October 11, 2005
PubMed
Summary

Protein hydrolysate formulas (HF) show potential for preterm infant feeding but lack evidence for atopy prevention. Further research is needed on their nutritional adequacy and long-term effects.

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Area of Science:

  • Neonatal nutrition
  • Pediatric gastroenterology

Background:

  • Protein hydrolysate formulas (HF) are used in infant feeding.
  • Their role in preterm newborns requires further clarification.

Purpose of the Study:

  • To review the role, indications, and nutritional adequacy of HF in preterm infants.
  • To assess the current evidence for HF in neonatal care.

Main Methods:

  • A comprehensive literature review was conducted.
  • Existing studies on protein hydrolysate formulas were analyzed.

Main Results:

  • No data support the use of HF for preventing atopy in infants.
  • HF may benefit early feeding in very-low-birthweight infants, but nutritional adequacy concerns remain.

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Conclusions:

  • Further research is essential to understand protein and mineral metabolism with HF.
  • Long-term effects, including neurodevelopmental outcomes, require investigation.