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Creutzfeldt-Jakob disease: Australian surveillance update to 31 December 2004
Genevieve M Klug1, Alison Boyd, Victoria Lewis
1Department of Pathology, The University of Melbourne, Victoria. gmjak@unimelb.edu.au
Insights
The Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR) monitors human prion diseases, including Creutzfeldt-Jakob disease (CJD), in Australia. Surveillance data from 1970 to 2004 provides key epidemiological findings.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- The Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR) was established in 1993.
- Surveillance was initiated following cases of iatrogenic Creutzfeldt-Jakob disease (CJD) linked to human pituitary hormones.
- The registry monitors all human prion diseases, also known as transmissible spongiform encephalopathies (TSEs).
Purpose of the Study:
- To present epidemiological findings on human prion diseases in Australia.
- To summarize data collected by the ANCJDR from 1970 to December 31, 2004.
Main Methods:
- Retrospective ascertainment of cases from 1970.
- Ongoing prospective surveillance of all human prion diseases.
- Data analysis of epidemiological trends.
Main Results:
- The ANCJDR has collected and analyzed data on prion diseases in Australia.
- Epidemiological findings cover the period from 1970 to 2004.
Conclusions:
- The ANCJDR plays a crucial role in monitoring prion diseases in Australia.
- The registry's surveillance efforts provide essential epidemiological data for public health.
Abstract:
The Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR) was established in October 1993 after the identification of probable iatrogenic CJD in recipients of human pituitary hormones. Since this time and with the recommendations of the Allars inquiry into CJD in Australia, the registry has performed surveillance of CJD in Australia with retrospective ascertainment to 1970 and ongoing prospective ascertainment of all human prion diseases or transmissible spongiform encephalopathies (TSEs). Prion diseases include CJD, Gerstmann-Straussler-Scheinker syndrome, fatal familial insomnia and Kuru. This brief summary presents the epidemiological findings of the ANCJDR based on data from 1970 to 31 December, 2004.
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