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Updated: Aug 15, 2026

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
Published on: January 20, 2019
[Plasma cell leukaemia]
C Rodriguez1, J-C Pont, I Gouin-Thibault
1Laboratoire d'hématologie, Groupe hospitalier Charles Foix Jean Rostand, Ivry Sur Seine.
Abstract:
We report a case of primary plasma cell leukaemia, with an absolute count of plasma cells of 53 Giga/L, diagnosed in a 83-year-old woman. The patient's condition improved, with no circulating plasma cells after 3 weeks of treatment, in response to the combination of thalidomide and dexamethasone administered for 5 days followed by thalidomide alone. The clinical presentation, the morphological, flow cytometric and pathophysiological characteristics of the plasma cell leukaemia and the treatment are summarised in this paper.
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