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Neoplastic transformation by the gep oncogene, Galpha12, involves signaling by STAT3

R N Kumar1, S K Shore, N Dhanasekaran

  • 1Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, 3307 N. Broad Street, Philadelphia, PA 19140, USA.

Oncogene
|October 26, 2005
PubMed
Summary

The Galpha(12) oncogene activates signal transducer and activator of transcription 3 (STAT3) signaling. This pathway involves multiple kinases and is critical for Galpha(12)-mediated neoplastic cell growth and transformation.

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