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[A study of bacterial meningitis in Hokkaido between 1999 and 2003]

Hiroshi Sakata1

  • 1Department of Pediatrics, Asahikawa Kosei Hospital.

Kansenshogaku Zasshi. the Journal of the Japanese Association for Infectious Diseases
|October 27, 2005
PubMed

Insights

Bacterial meningitis in children is most common in those under five years old. Streptococcus pneumoniae infections led to a higher rate of poor prognosis compared to Haemophilus influenzae.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Context:

  • Bacterial meningitis remains a significant cause of childhood morbidity and mortality.
  • Understanding regional incidence and causative agents is crucial for public health interventions.
  • This study examines pediatric bacterial meningitis in Hokkaido, Japan, from 1999-2003.

Purpose:

  • To determine the incidence and epidemiology of bacterial meningitis in children in Hokkaido, Japan.
  • To identify the primary causative pathogens and their distribution.
  • To assess the mortality and sequelae associated with pediatric bacterial meningitis.

Summary:

  • A questionnaire-based evaluation of 83 children with bacterial meningitis across 67 institutions in Hokkaido, Japan (1999-2003).
  • Incidence rates were 6.3 per 100,000 children/year for those under 5. Major pathogens included Haemophilus influenzae (3.7), Streptococcus pneumoniae (1.4), and Streptococcus agalactiae (0.8) in children under 5.
  • The overall case mortality rate was 4.8%, with 25.3% experiencing sequelae. Streptococcus pneumoniae infections showed a higher frequency of poor prognosis (55.6%) compared to Haemophilus influenzae (21.6%).

Impact:

  • Provides critical epidemiological data on pediatric bacterial meningitis in a specific Japanese region.
  • Highlights the significant burden of disease in infants and young children.
  • Informs targeted prevention and treatment strategies, emphasizing the differential prognosis based on causative agents.

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