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Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs
Published on: December 27, 2016
Mechanism underlying the effect of myelopeptides on lymphocyte proliferation in vitro
T V Gavrilova1, S V Gein, T A Pogudina
1Analytical Laboratory, Institute for Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm.
Bulletin of Experimental Biology and Medicine
|October 29, 2005
Abstract:
We studied the role of monocytes in the effect of myelopid and myelopeptides MP-1, MP-3, MP-5, and MP-6 on functional activity of peripheral blood lymphocytes in the reaction of blast transformation. Myelopeptides MP-1, MP-3, and MP-6 suppressed blast transformation of lymphocytes. The effect depended on the presence of monocytes in a cell culture.
