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Updated: Jul 30, 2026

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Published on: March 24, 2017
Dexamethasone suppresses human interleukin-5 gene promoter
V A Mordvinov1, C C Kok, E Arthaningtyas
1Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk. mordvin@bionet.nsc.ru
Abstract:
Synthetic glucocorticoid dexamethasone suppressed interleukin-5 gene expression in PER-117 human T cells at the level of transcription. The conserved lymphokine element 0 in the interleukin-5 gene promoter context served as a target for dexamethasone.
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