[The results of surgery on HIV carriers with urinary system disease]
Wei-guo Huang1, Le-shen Yao, Rong Yang
1Department of Urology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medicine College, Nanjing, Jiangsu 210008, China.
Insights
Surgery on HIV carriers with urinary diseases requires careful timing based on CD4+ T lymphocyte counts. Highly active antiretroviral therapy (HAART) is crucial before and after operations to manage human immunodeficiency virus (HIV) and improve outcomes.
Area of Science:
- Urology
- Infectious Diseases
- Surgical Oncology
Context:
- Surgical management of urinary system diseases in human immunodeficiency virus (HIV) infected individuals presents unique challenges.
- Optimal timing and therapeutic strategies are critical for successful surgical outcomes in this patient population.
Purpose:
- To evaluate surgical outcomes and identify key characteristics for performing operations on HIV carriers with urinary system diseases.
- To summarize surgical experiences with 41 HIV-positive patients undergoing urological procedures.
Summary:
- Forty-one HIV carriers with urinary diseases underwent surgery after receiving highly active antiretroviral therapy (HAART).
- Thirty-one patients recovered well, while four died of acquired immunodeficiency syndrome (AIDS), particularly those with low CD4+ T lymphocyte counts (<0.2 x 10(9)/L) undergoing major resections.
- Endourologic surgery and laparoscopy are recommended; careful monitoring of CD4+ T lymphocyte counts is essential for perioperative management.
Impact:
- Highlights the importance of HAART and CD4+ T lymphocyte monitoring for optimizing surgical interventions in HIV-positive patients.
- Emphasizes the need for precautions against occupational infections among healthcare workers during procedures on HIV carriers.
- Informs surgical decision-making and patient selection for urological procedures in the context of HIV infection.
Objective:
To approach characteristics of performing operation on HIV carriers with urinary system diseases.
Methods:
To summarize author's experiences of surgery on 41 HIV carriers suffering urinary system diseases abroad from April 1996 to May 2004.
Results:
The 41 HIV carriers received HAART and were performed with corresponding operations, followed up from 4 to 30 months post-operatively. The 31 carriers have recovered well up to date, while 4 carriers died of AIDS. Among them, 2 patients with penis cancer who received a partial peotomy and a patient with renal tuberculosis receiving left nephrectomy were died of AIDS within 4-8 months after operations whose CD4+ T lymphocyte number was below 0.2 x 10(9)/L.
Conclusion:
Prior to operation, HIV carriers should receive HAART ordinarily to control copy of the virus. The CD4+ T lymphocyte number is important for selecting a proper time for operation and deciding the further after surgery. We also take note to CD4+ T lymphocyte number to monitor progress of the AIDS. For those HIV carriers, endourologic surgery and laparoscopy should be taken so far as possible. Meanwhile, medical stuffs must pay more attention to preventing occupational infection during surgery.
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