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Updated: Aug 14, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
[Asbestos-related pleural plaques: a literature review]
G S P Meirelles1, J I Kavakama, D Jasinowodolinski
1Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil. gustavo.meirelles@fleury.com.br
Abstract:
Pleural plaques (PP) are considered to be hallmarks of asbestos exposure. They constitute focal thickenings of the pleura and are commonly seen in patients without lung disease. They can involve parietal, diaphragmatic and mediastinal pleura. Chest x-ray is frequently used for PP diagnosis, but computed tomography, especially when used the high-resolution technique, is the imaging exam with the greatest sensibility and specificity. PP are almost always asymptomatic, but there are some controversial about their relationship with asbestos exposure indexes, pulmonary functional alterations and risk of neoplasias.
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