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Updated: Aug 14, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
Chemoprevention: a primary cancer prevention strategy
Judith J Smith1, Patricia Tully, Rose Mary Padberg
1Department of Helth and Human Services, National Institutes of Health, National Cancer Institute, Division of Cancer Prevention, Bethesda, MD, USA. judiths@mail.nih.gov
Objectives:
To review cancer chemoprevention clinical trials, and to discuss associated roles, responsibilities, and challenges for nursing.
Data Sources:
Journal articles, textbooks, and government reports.
Conclusion:
Chemoprevention offers a promising approach to primary cancer prevention for a variety of organ systems. Candidate agents are rigorously evaluated for safety and efficacy through the chemoprevention clinical trials process.
Implications For Nursing Practice:
Chemoprevention is an emerging discipline in which complex clinical trials are being conducted. Nurses play key roles in planning, coordinating, and implementing these studies.
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