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Viral arthritis
Leonard H Calabrese1, Stanley J Naides
1Department of Rheumatic and Immunologic Diseases, The Cleveland Clinic, Cleveland, OH 44195, USA. calabrl@ccf.org
Infectious Disease Clinics of North America
|November 22, 2005
Summary
Viruses can cause acute or chronic arthritis through complex mechanisms influenced by host and viral factors. This review explores viral arthritis, including parvovirus B19 infections.
Area of Science:
- Virology
- Immunology
- Rheumatology
Background:
- Viral infections are common and can lead to various health issues.
- Some viruses cause acute, self-limiting illnesses, while others establish latency or chronic infections.
- The precise mechanisms by which viruses induce arthritis are not fully understood.
Purpose of the Study:
- To review the complex role of viruses in the development of acute and chronic arthritis.
- To discuss the diverse mechanisms underlying viral arthritis.
- To highlight specific viral causes, such as parvovirus B19.
Main Methods:
- Literature review of viral arthritis.
- Analysis of host and viral factors in pathogenesis.
- Discussion of clinical presentations and mechanisms.
Main Results:
- Viral infections are a significant, though complex, factor in arthritis development.
- Both acute and chronic arthritis can be triggered by viral agents.
- Host immune response and viral characteristics significantly influence disease outcome.
Conclusions:
- Viruses play a multifaceted role in causing arthritis.
- Understanding viral arthritis mechanisms is crucial for effective management.
- Parvovirus B19 serves as a key example of a virus-induced arthritic condition.