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Corticosteroids after preterm premature rupture of membranes
1Department of Obstetrics and Gynaecology, University of Dublin, Trinity College, Coombe Lying-in Hospital, Ireland.
Obstetrics and Gynecology Clinics of North America
|June 1, 1992
Abstract:
A review of all relevant randomized controlled trials provides strong evidence that corticosteroid therapy causes a significant reduction in respiratory distress syndrome (RDS) in preterm babies overall. This reduction in RDS is accompanied by a reduced incidence of neonatal death, intraventricular hemorrhages, and necrotizing enterocolitis. These benefits are also seen in cases of PROM. Corticosteroid therapy in PROM is associated with a trend toward an increase in neonatal infection.