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Updated: Feb 14, 2026

Derivation of a Human Brain Organoid with Microglia Development
Published on: January 17, 2025
Requirements for room temperature shimming of the human brain
Stuart Clare1, John Evans, Peter Jezzard
1Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, UK. stuart@fmrib.ox.ac.uk
Abstract:
Room temperature (RT) shims are used routinely in MRI to remove global and local B(0) field inhomogeneity introduced by the subject. Most clinical scanners use only second-order spherical harmonic terms, but with the increasing availability of very high field systems, third- and fourth-order terms are a serious consideration. However, choosing appropriate coil strengths is of critical importance in shim coil design since overspecification of the shim strengths can lead to a variety of problems, including shim coil self-resonance. In this study B(0) field map data collected over a period of 6 months (over 400 brain volumes) were analyzed to find the characteristic B-fields required to shim these brains. These data can be used to specify the coil requirements to effectively shim the human brain.
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