Single-photon imaging at 20,000 frames/s
Related Experiment Video
Updated: Aug 14, 2026

Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment
Published on: January 6, 2026
1Dipartimento Elettronica e Informazione, Politecnico di Milano, Italy. zappa@elet.polimi.it
Abstract:
A complete two-dimensional imaging system based on a silicon monolithic array of 60 single-photon counters is presented. The fabricated solid-state array is rugged and operates at low voltages. Detection efficiency is higher than 40% in the visible range, and cross talk among 50 microm pixels is lower than 10(-4). The complete system provides a maximum throughput of 20 kframes/s with truly parallel readout and nanosecond gating, thanks to the use of an integrated active quenching circuit for each pixel of the array. We report optical and electrical characterizations of the whole imaging system.

