Related Experiment Video
Updated: Aug 14, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Olfactory neuroblastoma in an old patient. Report of a case]
V Pino Rivero1, G Trinidad Ruíz, A González Palomino
1Complejo Hospitalario Infanta Cristina, Facultativo Especialista de Otorrinolaringología, Badajoz. vicentepinorivero@terra.com
Abstract:
Olfactory neuroblastoma or esthesioneuroblastoma is a rare embrionary tumor, much more in old patients, which uses to present as a pollipoid mass with nasal obstruction, epistaxis and anosmia of long evolution. We report the case of a 82-year-old male with such symptoms diagnosed by biopsy as neuroblastoma class III according the histologic Hyams grading. Due to the age of the patient and grade of the tumor we did not perform surgery and, although a chemotherapy-radiotherapy treatment was suggested, the patient was not agree with it and he has not been attended or followed in our consulting rooms.