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Peno-gingival lichen planus.

Massimo Petruzzi1, Michele De Benedittis, Luca Pastore

  • 1Department of Odontostomatology and Surgery, University of Bari, Bari, Italy. petruzmf@tin.it

Journal of Periodontology
|December 8, 2005
PubMed
Summary
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Peno-gingival lichen planus in males, though rare, can be managed with topical clobetasol propionate. Early diagnosis and multidisciplinary care are crucial for symptom improvement and preventing complications.

Area of Science:

  • Dermatology
  • Urology
  • Oral Medicine

Background:

  • Simultaneous oral and genital lichen planus in males is rare and challenging to diagnose.
  • Established treatment guidelines and prevalence data are lacking, with management often based on anecdotal evidence.
  • This study details eight cases of peno-gingival lichen planus and proposes a management algorithm.

Purpose of the Study:

  • To present the clinical characteristics of peno-gingival lichen planus in males.
  • To propose a management algorithm for this rare condition.
  • To review current treatment options based on available evidence.

Main Methods:

  • Collected personal medical history for eight male patients.
  • Performed clinical examinations of oral and genital mucosae, obtained pathology, and recorded treatment history.

Related Experiment Videos

  • Initiated treatment with topical clobetasol propionate, switching to topical cyclosporine for non-responders, and evaluated outcomes at 8 weeks. Conducted a literature review.
  • Main Results:

    • Five patients exhibited gingival lesions consistent with lichen planus.
    • All eight patients had glans penis involvement.
    • Seven out of eight patients responded to treatment; oral candidiasis was the sole side effect.

    Conclusions:

    • Atrophic-erosive gingival lichen planus in males may indicate concurrent genital lichen planus.
    • Multidisciplinary management and prompt treatment are essential to alleviate symptoms and prevent sequelae.
    • Further research and therapeutic trials are needed for peno-gingival lichen planus, considering potential squamous cell carcinoma risk.