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Monilethrix: improvement with acitretin
Yelda Karincaoglu1, Basak K Coskun, Muammer E Seyhan
1Department of Dermatology, School of Medicine, Inonu University, Malatya, Turkey.
American Journal of Clinical Dermatology
|December 14, 2005
Summary
Monilethrix, a rare hair disorder, showed significant improvement with oral acitretin in a pediatric case. Symptoms recurred upon treatment cessation, indicating acitretin
Area of Science:
- Dermatology
- Genetics
- Pediatrics
Background:
- Monilethrix is a rare hereditary hair shaft anomaly.
- Currently, no definitive cure exists for Monilethrix.
- This condition significantly impacts hair structure and appearance.
Observation:
- A 7-year-old girl with Monilethrix was treated with oral acitretin.
- The patient presented with characteristic hair shaft abnormalities.
Findings:
- Oral acitretin treatment yielded excellent clinical and cosmetic results.
- Hair condition improved substantially during the course of therapy.
- Recurrence of symptoms was observed after acitretin discontinuation.
Implications:
- Acitretin shows potential as a therapeutic option for Monilethrix.
- Long-term management strategies may be necessary for sustained results.
- Further research into acitretin's efficacy and safety in Monilethrix is warranted.