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Breast cancer biomarkers
Jeffrey S Ross1, W Fraser Symmans, Lajos Pusztai
1Department of Pathology and Laboratory Medicine, Albany Medical College, Albany, New York 12208, USA.
Advances in Clinical Chemistry
|December 17, 2005
Summary
Understanding breast cancer has advanced significantly. This review covers current and new molecular markers for assessing prognosis and predicting treatment response in breast cancer patients.
Area of Science:
- Oncology
- Molecular Biology
- Genetics
Background:
- Breast cancer understanding has grown over 30 years.
- Epidemiology, clinical course, and biology are key research areas.
Purpose of the Study:
- To review ancillary tests for breast cancer prognosis.
- To discuss emerging molecular markers for treatment response prediction.
Main Methods:
- Literature review of existing ancillary tests.
- Analysis of emerging molecular markers in breast cancer.
Main Results:
- Ancillary tests provide prognostic information.
- Molecular markers show promise in predicting treatment outcomes.
Conclusions:
- Current and novel markers are crucial for personalized breast cancer care.
- Further research into molecular markers will refine treatment strategies.