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The many faces of PPARgamma

Michael Lehrke1, Mitchell A Lazar

  • 1Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, and The Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

Cell
|December 20, 2005
PubMed
Summary

Peroxisome proliferator-activated receptor gamma (PPARgamma) regulates metabolism and fat storage, contributing to obesity but also serving as a target for diabetes drugs. Selective modulation of PPARgamma may offer therapeutic benefits with reduced side effects.

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