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Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
Published on: November 27, 2019
[Acute liver failure following heat stroke]
A J Pardo Cabello1, M N Benticuaga Martínez, A Martín Moreno
1Servicio de Medicina Interna B, Hospital Clínico San Cecilio, Granada, Spain. apardoc02@hotmail.com
Anales De Medicina Interna (Madrid, Spain : 1984)
|January 3, 2006
Summary
Heat stroke can cause severe liver damage, sometimes requiring transplantation. This case highlights a runner
Area of Science:
- Sports Medicine
- Hepatology
- Critical Care Medicine
Background:
- Heat stroke is a serious condition with frequent hepatic involvement.
- Severe cases may necessitate liver transplantation.
- Athletes undertaking endurance events are at risk.
Observation:
- A 31-year-old male amateur runner experienced heat stroke during a marathon.
- The patient developed acute liver failure, rhabdomyolysis, renal failure, and coagulation impairment.
- Environmental factors like high temperature, exercise duration, and race altitude may have contributed.
Findings:
- The runner presented with multiple organ dysfunction secondary to heat stroke.
- Conservative management led to a favorable clinical course.
- The patient was discharged within a few days.
Implications:
- This case underscores the potential for severe, multi-organ complications from exertional heat stroke in athletes.
- Conservative treatment can be effective in managing heat stroke-related acute liver failure.
- Awareness of environmental risk factors is crucial for preventing heat stroke during endurance events.
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