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Updated: Aug 13, 2026

An Efficient and Rapid HPLC-QQQ-MS Method for the Quantitation of Tropane Alkaloids in Medicinal Plants
Published on: June 12, 2026
[Studies on the alkaloids from stem of Artabotrys hainanensis]
Chang-ri Han1, Guo-yuan Zhu, Guang-ying Chen
1Department of Chemistry, Hainan Normal University, Haikou 571158, China.
Objective:
To investigate the alkaloids from the stem of Artabotrys hainanensis.
Method:
Compounds in plant extracts were separated by silica gel and sephadex LH-20 column chromatography. Chemical structures were elucidated by chemical and spectral analyses including UV, 1H-NMR, 13C-NMR, ESIMS and ESI-MS-MS.
Result:
Eight alkaloids were isolated and identified as spinosine (1), 3-hydroxynornuciferine (2), juzirine (3), artabotrine (4), liridine (5), assimilobine (6), isococlaurine (7), N-demethylarmepavine (8).
Conclusion:
All alkaloids were isolated from this plant for the first time and compounds 1, 3, 7 and 8 were isolated from genus Artabotrys for the first time.
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