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[Cardiovascular system and aging].

H Saner1

  • 1Kardiovaskuläre Prävention und Rehabilitation, Klinik und Poliklinik für Kardiologie, Inselspital Bern und Kardiologische Praxis, Olten. hugo.saner@insel.ch

Therapeutische Umschau. Revue Therapeutique
|January 13, 2006
PubMed
Summary
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Aging significantly impacts cardiovascular health, increasing risks like hypertension and diabetes. Effective management involves lifestyle changes and optimized medications, with certain drugs like aspirin and statins proving beneficial in older adults.

Area of Science:

  • Cardiovascular Medicine
  • Gerontology
  • Vascular Biology

Context:

  • Aging is a primary risk factor for cardiovascular disease.
  • Age-related vascular changes include intima-media thickening and reduced vessel compliance.
  • Cardiac aging involves increased left ventricular mass and decreased diastolic function.

Purpose:

  • To review the cardiovascular changes associated with aging.
  • To discuss the role of lifestyle and medical interventions in managing cardiovascular risk in the elderly.
  • To evaluate the efficacy and safety of specific pharmacotherapies in older adults.

Summary:

  • Cardiovascular aging involves structural and functional changes in vessels and the heart.
  • Risk factors like hypertension and diabetes become more prevalent with age.

Related Experiment Videos

  • Prevention strategies include lifestyle modifications and evidence-based pharmacotherapy.
  • Antioxidant supplements lack evidence for preventing vascular aging.
  • Aspirin, beta-blockers, ACE-inhibitors, and statins play roles in cardiovascular prevention and management in the elderly.
  • Myocardial infarction in the elderly may present atypically; interventional therapy and cardiac rehabilitation are effective but require careful consideration of complication rates.

    • Impact:

    • Highlights the importance of risk factor management in aging populations.
    • Emphasizes the underutilization of certain medications in older patients.
    • Provides evidence for the continued efficacy of interventions like statins and cardiac rehabilitation in the elderly.
    • Informs clinical practice regarding cardiovascular care for aging individuals.