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Updated: Aug 13, 2026

Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction
Published on: March 7, 2013
[Hepaticocholedoch reconstruction by explants and autotransplants]
Abstract:
Authors have elaborated new method of surgical correction of hepaticocholedoch strictures. The experiments were carried out on 25 mongrel dogs of both sexes with body weight 15-25 kg. The surgical procedures were done under endotracheal ether narcosis. The hepaticocholedoch stricture was induced preliminarily in all animals. After the modelling, stricture was cut out, the anatomical integrity of the common bile duct was restored by autovein (n=10) and "GORE-TEX" vascular prosthesis (n=10). The performed investigations have shown that autovenous transplant was subjected to incrustation by bile salts, later on it became necrotic. Therefore the autovenous transplant could not be used in biliary reconstruction. The results of biliary reconstruction by "GORE-TEX" vascular prosthesis were promising. The "GORE-TEX" vascular prosthesis is well adapting with bile ducts tissue and do not incrust by bile salts.

