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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Synthesis of oximes under ultrasound irradiation
Ji-Tai Li1, Xiao-Liang Li, Tong-Shuang Li
1College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding 071002, PR China. orgsyn@mail.hbu.edu.cn
Abstract:
The condensation of aldehydes and ketones with hydroxylamine hydrochloride results oximes in 50.7-98.7% yields in EtOH under ultrasound irradiation. Compared with conventional methods, the main advantages of the present procedure are milder conditions, shorter reaction time and higher yields.
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