Pathophysiology, diagnosis and current management of chronic constipation

Area of Science:

• Gastroenterology
• Colorectal Surgery

Background:

• Chronic constipation is a widespread condition in Western societies.
• Most patients with constipation are managed effectively with initial conservative therapies.
• A subset of patients presents with severe or refractory constipation requiring further evaluation.

Purpose of the Study:

• To review modern principles in managing chronic constipation.
• To discuss therapeutic options for varying severities of constipation.
• To highlight the utility of specialized testing in refractory cases.

Main Methods:

• Review of current medical literature and clinical guidelines.
• Analysis of diagnostic approaches for chronic constipation.
• Synthesis of therapeutic strategies for constipation management.

Main Results:

• Conservative management is effective for most patients.
• Severe and refractory constipation may necessitate advanced diagnostic studies.
• Specific patient subgroups benefit from specialized interventions.

Conclusions:

• Effective management of chronic constipation depends on assessing severity.
• Colonic and anorectal function studies are valuable for refractory constipation.
• A comprehensive approach guides optimal therapy for chronic constipation.