Related Experiment Video
Updated: Aug 11, 2026
05:46
Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Published on: September 20, 2024
Long-term changes in corneal surface configuration after penetrating keratoplasty
Ken Hayashi1, Hideyuki Hayashi
1Hayashi Eye Hospital, and the Department of Ophthalmology, School of Medicine, Fukuoka University, Japan. hayashi-ken@hayashi.or.jp
American Journal of Ophthalmology
|February 7, 2006
Summary
Corneal shape and vision stabilize about six months after penetrating keratoplasty (PK). This study tracked corneal configuration and visual acuity changes for two years post-surgery.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Refractive Error Analysis
Background:
- Penetrating keratoplasty (PK) is a common surgical procedure to restore vision in patients with corneal opacity.
- Understanding the long-term changes in corneal surface and visual outcomes after PK is crucial for patient management and surgical planning.
Purpose of the Study:
- To investigate longitudinal changes in corneal surface configuration using Fourier analysis of videokeratography data.
- To assess long-term changes in visual acuity and refraction following penetrating keratoplasty.
Main Methods:
- An interventional case series involving 130 eyes undergoing PK with standard suture techniques.
- Videokeratography data analyzed via Fourier series harmonic analysis to quantify corneal power, regular astigmatism, and irregular astigmatism.
- Spectacle-corrected visual acuity and refraction were measured at multiple time points up to 24 months post-PK.
Main Results:
- Corneal spherical equivalent power stabilized by 1 month post-PK.
- Regular astigmatism decreased significantly up to 6 months, while irregular astigmatism reduced by 3 months, with both stabilizing thereafter.
- Spectacle-corrected visual acuity improved markedly by 3 months and remained stable up to 24 months, showing correlations with astigmatism components.
Conclusions:
- Corneal surface configuration demonstrates stability around 6 months after penetrating keratoplasty.
- Visual acuity stabilization occurs concurrently with corneal surface stability, typically by 6 months post-PK.
