Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mapping brain maturation.

Arthur W Toga1, Paul M Thompson, Elizabeth R Sowell

  • 1Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, 635 Charles E. Young Drive South, Suite 225, Los Angeles, CA 90095-7332, USA. toga@loni.ucla.edu

Trends in Neurosciences
|February 14, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2015
Same author

Development of the human fetal hippocampal formation during early second trimester.

NeuroImage·2015
Same author

2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2015
Same author

Sharing data in the global alzheimer's association interactive network.

NeuroImage·2015
Same author

Imaging in StrokeNet: Realizing the Potential of Big Data.

Stroke·2015
Same author

The Image and Data Archive at the Laboratory of Neuro Imaging.

NeuroImage·2015
Same journal

Building neuroscience capacity in low- and middle-income countries: Lessons from Ghana.

Trends in neurosciences·2026
Same journal

Emulating the periodic table: A unified list of CNS terms and abbreviations for humans and experimental animals.

Trends in neurosciences·2026
Same journal

From chromatin dynamics to brain disease: Polycomb-Trithorax mechanisms in neurodevelopment.

Trends in neurosciences·2026
Same journal

Striatum regulates the cortex via the basal forebrain cholinergic system: A role for substance P.

Trends in neurosciences·2026
Same journal

A large brain adds new types of neurons: Molecular and functional signatures of spindle neurons in the human neocortex.

Trends in neurosciences·2026
Same journal

Exercise as a regulator of glymphatic function.

Trends in neurosciences·2026
See all related articles

Neuroimaging reveals human brain maturation, tracking structural changes in healthy children and those with developmental disorders like ADHD. This research connects brain development to cellular processes and cognitive changes.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Medical Imaging

Background:

  • Human brain maturation is a lifelong, intricate process.
  • Neuroimaging techniques, particularly structural magnetic resonance imaging (MRI), allow detailed examination of brain development.
  • Longitudinal studies are crucial for reconstructing the timeline and anatomical progression of development.

Purpose of the Study:

  • To review recent advancements in neuroimaging studies of human brain development.
  • To detail cortical and subcortical changes in healthy children.
  • To contrast normal development with abnormal changes in conditions like early-onset schizophrenia, fetal alcohol syndrome, ADHD, and Williams syndrome.

Main Methods:

  • Utilizing longitudinal structural magnetic resonance imaging (MRI) data.

Related Experiment Videos

  • Analyzing cortical and subcortical brain structures.
  • Comparing developmental trajectories in healthy subjects versus clinical populations.

    • Main Results:

    • Documented typical patterns of cortical and subcortical maturation in children and adolescents.
    • Identified distinct structural alterations associated with specific neurodevelopmental disorders.
    • Established correlations between structural brain changes and underlying cellular processes.

    Conclusions:

    • Neuroimaging provides critical insights into the complexities of human brain maturation.
    • Understanding developmental trajectories aids in characterizing and potentially diagnosing neurodevelopmental disorders.
    • Linking structural changes to cellular and cognitive functions enhances our comprehension of brain development throughout childhood and adolescence.