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Establishment of an oocyte donor program. Donor screening and selection.
M M Quigley1, R L Collins, L R Schover
1Department of Gynecology, Cleveland Clinic Foundation, Ohio 44195-5037.
Annals of the New York Academy of Sciences
|January 1, 1991
Summary
Oocyte donation through a dedicated volunteer program offers a successful IVF treatment for infertility. However, donor availability and psychological factors may limit its widespread application.
Area of Science:
- Reproductive Medicine
- In Vitro Fertilization (IVF)
- Oocyte Donation
Background:
- In vitro fertilization (IVF) using donated oocytes is a successful infertility treatment.
- Existing oocyte donation methods (e.g., excess IVF oocytes, surgical retrieval) present ethical and practical challenges.
- A novel program utilizing anonymous volunteers for oocyte donation was established.
Purpose of the Study:
- To describe the establishment and outcomes of a new oocyte donation program.
- To evaluate the screening, donation process, and preliminary success rates.
- To explore the psychological aspects and motivations of oocyte donors.
Main Methods:
- Recruitment and screening of anonymous oocyte donors.
- Ovarian stimulation, monitoring, and oocyte recovery procedures for donation.
- Psychological evaluation of potential donors.
Main Results:
- The oocyte donation program achieved successful IVF outcomes.
- Donors underwent rigorous screening and education, yet a significant percentage withdrew or were disqualified.
- Psychological evaluations revealed complex backgrounds and diverse motivations among donors.
Conclusions:
- IVF with donated oocytes is highly effective for specific infertility cases.
- The program's success is tempered by challenges in donor recruitment and retention.
- Further research into the psychological dynamics of oocyte donation is recommended.