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Severe hypocalcemic tetany and respiratory failure in an infant given oral phosphate soda
Kiran Hebbar1, James D Fortenberry, John S Parks
1Division of Critical Care, Children's Healthcare of Atlanta at Egleston, Atlanta, GA 30322, USA. Kiran.hebbar@choa.org
Insights
Oral phosphate laxatives can cause severe electrolyte disturbances in infants. An infant experienced life-threatening hypocalcemia and respiratory failure after accidental ingestion, highlighting risks in children.
Area of Science:
- Pediatrics
- Toxicology
- Gastroenterology
Background:
- Oral phosphate preparations are commonly used for constipation and bowel preparation in adults.
- Their use in children is generally not recommended due to risks of severe electrolyte disturbances.
Observation:
- A 7-week-old infant accidentally ingested an over-the-counter oral phosphate preparation intended for adults.
- The infant subsequently developed profound hypocalcemia and hyperphosphatemia.
Findings:
- The infant experienced life-threatening tetany and respiratory failure.
- Mechanical ventilation and intravenous calcium gluconate were required for recovery.
Implications:
- Pediatricians and healthcare providers must be aware of the potential misuse of adult oral phosphate laxatives in children.
- This case underscores the critical need for caution and appropriate patient education regarding phosphate preparation safety in pediatric populations.
Abstract:
Oral phosphate preparations are used for constipation and bowel preparation in adults but with potential for fatal electrolyte disturbances. Use in children is not recommended due to similar concerns. We report a 7-week-old infant who received an over-the-counter oral phosphate preparation. He developed profound hypocalcemia, hyperphosphatemia, life-threatening tetany, and respiratory failure requiring mechanical ventilation and intravenous calcium gluconate for recovery. Practitioners should be aware of the availability and potential misuse of adult oral phosphate laxative products for children.
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