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Published on: March 24, 2020
Strabismus in Down syndrome
Nazife Sefi Yurdakul1, Seyda Ugurlu, Ahmet Maden
1Izmir Atatürk Education and Research Hospital, Department of Ophthalmology, Izmir, Turkey.
Journal of Pediatric Ophthalmology and Strabismus
|February 24, 2006
Summary
Strabismus, particularly esotropia, and hypermetropia are common in individuals with Down syndrome. Early detection and management of these eye conditions can enhance patient quality of life.
Area of Science:
- Ophthalmology
- Genetics
Background:
- Down syndrome is associated with various health complications, including ocular abnormalities.
- Refractive errors and strabismus are frequently observed in this population.
Purpose of the Study:
- To investigate the prevalence of refractive errors and the clinical characteristics of strabismus in patients with Down syndrome.
- To compare refractive errors and associated conditions between strabismic and non-strabismic patients with Down syndrome.
Main Methods:
- A cohort of patients with Down syndrome underwent comprehensive eye examinations.
- Ocular alignment was assessed using cover tests and corneal reflex tests.
- Cycloplegic refraction, dilated fundus examination, and comparison of refractive errors were performed.
Main Results:
- Eleven percent of patients with Down syndrome had strabismus, predominantly esotropia (10%).
- Acquired esotropia was linked to significant refractive errors and anisometropia.
- Hypermetropia was more prevalent in patients with strabismus (P < .05).
Conclusions:
- Esotropia and hypermetropia are significant findings in patients with Down syndrome.
- Timely diagnosis and treatment of strabismus and refractive errors are crucial for improving visual outcomes and quality of life.
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